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Promega cgh array p3
CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial <t>P3</t> GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests
Cgh Array P3, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cgh+array+p3/pmc05691136-387-16-24?v=Promega
Average 90 stars, based on 1 article reviews
cgh array p3 - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors"

Article Title: The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

Journal: Nature Communications

doi: 10.1038/s41467-017-01686-y

CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial P3 GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests
Figure Legend Snippet: CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial P3 GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests

Techniques Used: Expressing, Staining, Immunofluorescence, Membrane, Laser-Scanning Microscopy, Comparison, MANN-WHITNEY



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Promega cgh array p3
CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial <t>P3</t> GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests
Cgh Array P3, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cgh+array+p3/pmc05691136-387-16-24?v=Promega
Average 90 stars, based on 1 article reviews
cgh array p3 - by Bioz Stars, 2026-07
90/100 stars
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CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial P3 GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests

Journal: Nature Communications

Article Title: The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

doi: 10.1038/s41467-017-01686-y

Figure Lengend Snippet: CXCR3 and LRP1 expression in glioblastoma samples from patients. a HE staining was performed in the experimental mouse intracranial P3 GBM model that recapitulates the regional heterogeneity of gliomas. (1) healthy brain, (2) angiogenic part, and (3) invasive part. b Immunofluorescence with anti-vimentin (sc-6260 clone V9, Santa Cruz) ( λ = 547 nm) and anti-LRP1 (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) antibodies on tissue from healthy mouse brain, angiogenic, or invasive part of the P3 GBM tumor. Scale: 5 µm. c Graph depicts the quantification of LRP1 expression in angiogenic and invasive areas ( n = 30). *** P <0.001. d MRI image from a representative glioblastoma (GBM) patient. Samples were taken intraoperatively with the aid of neuronavigation from the tumor angiogenic core (contrast enhancement ring) and the infiltrative area (T1 hypointense abnormality). e Immunofluorescence with anti-CXCR3 (antibody 2ar1, Abcam) and anti-LRP1 antibodies (antibody 2703-1 for LRP1β, Epitomics) ( λ = 488 nm) on tissue samples from either the angiogenic or invasive part of the tumor. Membrane and/or perinuclear localization of CXCR3 and LRP1 were observed at a ×630 magnification with phase contrast brightfield under a confocal laser scanning microscope (Nikon Eclipse ti). Scale: 5 μm. Graphs (protein intensity, n = 30, and CXCR3 localization, n > 300) depict the quantification from three different patients. NS non-significant. *** P <0.001. Statistical comparison between two groups was performed using the Mann–Whitney U -test. Multiple comparisons were performed with one-way analysis of variance, followed by Bonferroni post hoc tests

Article Snippet: All cells used for phenotypic and functional studies have been further characterized more in detail by cGH array (P3) and by cell authentification using Promega Powerplex21 Kit (Eurofins, GE) (cell lines).

Techniques: Expressing, Staining, Immunofluorescence, Membrane, Laser-Scanning Microscopy, Comparison, MANN-WHITNEY